Unusual Parkinson's symptom found that can be heard years before signs appear

13 May 2023 , 05:59
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One of the main signs to watch out for is a voice becoming monotone and softer (Image: Getty Images)
One of the main signs to watch out for is a voice becoming monotone and softer (Image: Getty Images)

Scientists have uncovered the early signs of Parkinson's disease, following a study using zebra finch birds.

Parkinson's disease is a condition that affects the brain, causing problems with uncontrollable movements including shaking, tremors and stiffness that get worse over time.

Caused by a loss of nerve cells in part of the brain, it's the fastest growing neurological condition in the world, and currently there is no cure, the Daily Record reports.

According to Parkinson's UK, there were around 145,000 people living with a Parkinson's diagnosis in the UK in 2020.

While tremors and slow movement are the main signs of Parkinson's disease, scientists have discovered a symptom that could present long before a person is diagnosed.

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Unusual Parkinson's symptom found that can be heard years before signs appearA loss of nerve cells in part of the brain causes Parkinson's (Getty Images/Cultura RF)

Researchers found a link between a Parkinson's disease gene and vocal issues, leading to a soft monotonous voice.

These vocal symptoms often appear much earlier - sometimes decades - before movement-related issues, according to a study conducted on songbirds by neuroscientists in the lab of Julie E Miller, assistant professor at the University of Arizona.

Studying the zebra finch, whose brain that deals with speech and language is also organised very similarly to humans, scientists found the gene did affect song production.

The birds with the gene sang less after two months, and they sang less at the start of a song session three months after receiving the gene. Their vocalisations were also softer and shorter - findings similar to what is seen in Parkinson's disease.

Unusual Parkinson's symptom found that can be heard years before signs appearOne primary motor symptom is bradykinesia, which can lead to vocal variation and a 'mask-like' expression (Getty Images/Collection Mix: Subjects RF)

This findings are backed up by recent research, which developed an automated screening method that can distinguish between the voices of Parkinson's patients and healthy individuals.

The Scientists at Providence Saint John’s Health Center in Santa Monica, California found their model could predict 80 to 90 per cent of voices from those with Parkinson's Disease.

The American Parkinson Disease Association (APDA), who state there are four primary motor symptoms of the condition - one of which being bradykinesia (slow movement).

Unusual Parkinson's symptom found that can be heard years before signs appearParkinson's is the fastest growing neurological condition (Getty Images/Science Photo Library RF)

Delving into bradykinesia, this common symptom of Parkinson's disease could affect the way a person sounds. The voice may become softer, or it may start off strong and then fade away.

There could be a loss in the normal variation in volume and emotion in the voice - it could make someone sound monotone.

In advanced stages of Parkinson's, the person's speech may become rapid, with the words crowded together; stuttering may also occur.

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Bradykinesia can be demonstrated by a reduced or "mask-like" expression of the face. This is when you're unable to decipher how a person is feeling, as they seem expressionless.

Sophie Law

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