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Madeline Soto vanished on Monday, February 26, after her mother's boyfriend reportedly dropped her off at Peace United Methodist Church on Town Loop Boulevard, just a few blocks away from Hunter's Creek Middle School

A total of 45% of San Mateo residents reported experiencing loneliness, compared to the national average of 17% in the US and it has now been declared a public health emergency

Donald Trump won the Iowa Caucus by a massive 30-point margin, destroying second-place finisher Florida Gov. Ron DeSantis and forcing fourth-place vote-getter entrepreneur Vivek Ramaswamy to drop out of the race

Perry High School shooter Dylan Butler is believed to have been messaging other Discord users just minutes before he opened fire at the Iowa high school, telling them he was 'gearing up'

This is England and Line of Duty actress Vicky McClure was made an MBE for services to drama and charity at a ceremony held at Windsor Castle on Tuesday

The body of Brandon Smith, 17, was found on Sunday in Georgia as those who knew him described the teenager as an 'all-round amazing kid' and asked people to pray for his family

All the nasty winter bugs are returning and will soon be spreading like wildfire through your child’s school classroom. Here are all the most common diseases for your child and how to tell them apart

Ignoring what seemed to be minor ailments because they were expected for someone who lived a glamorous life on the road could have had fatal consequences

A mayor who was an upstanding member of his community and church preacher took his own life after being cruelly outed as having a transgender alter-ego that allegedly wrote violent fantasy fiction

A simple test you can do at home could provide an insight into your life expectancy - and signal underlying health issues - claims NBC News' Doctor Natalie Azar

Trump’s legal woes continue as he has begun battling the first of his four indictments. But one insider claims the former President is 'unfazed and happy,' despite his social media outbursts

The 14-year-old trans girl, named only as Ren had been forced to live two lives, hiding who she really was at home where she lived with her mother, before eventually skipping school to take. Greyhound bus 300 miles away from home

The comedian has reportedly been telling friends he's struggling with Jada speaking about his past interactions with her as she promotes her new book

The family of a girl kidnapped in New York State have spoken of their relief after their daughter was found. A suspect was arraigned after leaving fingerprints on a ransom note left for the girl’s parents

Lahaina's iconic banyan tree has emerged as a symbol of hope after wildfires spread rapidly throughout the area, decimating the historic Front Street as people lost homes and loved ones

NBC's Today show contributor Jill Martin shares her health journey following her breast cancer diagnosis and double mastectomy urging all of her fans to receive genetic testing

Lizzo's dancers claim they feared that their jobs could be in jeopardy, while working for the global megastar, if they didn't do what she said and what she wanted

Bodycam footage shows the officers demanding a black family, including two boys aged 12 and 13, exit the vehicle before on of the youngsters is handcuffed, to his mother's horror

Christian Shearhod, who shares updates about his life on TikTok, said that he wants his three-year-old son, Ashton, to enjoy his childhood without "strict gender norms"

Nathan Carman, 28, was facing eight charges in relation to his mother's death who drowned while on a boating trip with her son - he also faced charges over the death of his grandfather

Chuck Todd has announced that he is leaving his role of moderating the NBC political panel show Meet the Press, with him noting that he 'promised his family' he wouldn't let work consume him

Lesley Swick Van Ness, news anchor at WGEM-TV, has died at the age of 42 after falling ill while on holiday in Florida with her husband and their two young sons

Presenter Jenna Wolfe has opened up on her operations after testing positive for the BRCA1 cancer gene which left her with a larger chance of developing cancer

Shohei Ohtani struck out his Los Angeles Angeles team-mate Mike Trout in a magical conclusion that secured Japan’s third World Baseball Classic win against the defending champions Team USA

Beaches in the path of the gargantuan blob's path are bracing for being buried under three feet of rotting seaweed - and it's not just tourism that could be threatened